Zoological and Entomological Letters
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P-ISSN: 2788-8428, E-ISSN: 2788-8436

2024, Vol. 4, Issue 2, Part A


Evaluation of oil vaccines of avian influenza H5 virus in layer by hemagglutination test


Author(s): Hasan Muwafaq Ali and Raed Hussain Salih Rabee

Abstract: Background: Two strains of the influenza A virus, known as high-path and low-path, produce the extremely infectious disease known as avian influenza. Typically given as an intramuscular or subcutaneous injection, chicken vaccines aim to lessen the severity and spread of diseases. Large-scale vaccination programs might make use of live-attenuated vaccines, which mimic a disease in the body to elicit a robust immune response. This research aimed to evaluate the effectiveness of oil vaccinations against the H5 virus of avian influenza in layers using the hemagglutination test. Methods: This study evaluated the immunity of Avian Influenza virus (H5) in Iraqi Layers chickens (LOHMAN Brown) after vaccination with the AIV Killed Oil Vaccine. 192 chicks were divided into 4 treated groups and vaccinated at 10, 70, 110, and 210 days. Blood serum was taken for titration of AI by HI for determination of immunity.Results: Day 1 Initial Measurements, all study groups showed similar HI values. 30 days post-Intervention, significant changes were found, with the MEVAC group displaying the highest level (13.33±7.10). The greatest level (58.67±7.10) was still shown by the MEVAC group 50 days after the intervention. The greatest level, 109.33±58.62, was maintained by the MEVAC group 70 days after the intervention. At every time point tested between 90 and 210 days after the intervention, the MEVAC group showed the greatest levels of HI (176.00±72.84 at 90 days and 1194.67±398.59 at 210 days).Conclusion: MEVAC vaccine was significantly more effective than the other groups over time, as evidenced by the consistently higher levels in HI tests across all measured intervals. This suggests a strong and sustained immune response associated with the MEVAC vaccine.

Pages: 34-43 | Views: 124 | Downloads: 51

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Zoological and Entomological Letters
How to cite this article:
Hasan Muwafaq Ali, Raed Hussain Salih Rabee. Evaluation of oil vaccines of avian influenza H5 virus in layer by hemagglutination test. Zool Entomol Lett 2024;4(2):34-43.

Zoological and Entomological Letters