2024, Vol. 4, Issue 2, Part A
Study of protective role of ascorbic acid against betamethasone in female guinea pigs (Cavia porcellus)
Author(s): Alaa Najee Salih
Abstract: The objective of this study was to detected the role of Ascorbic acid against Betamethasone in female guinea pigs, the experimental design involved the use of 40 female guinea pigs which are divide into four groups: 1-Control group (C1). 2- Ascorbic acid 500 mg/ kg group (C2). 3- Betamethasone 0.5 mg/kg B.W group (C3). 4-Ascorbic acid and Betamethasone 0.5 mg/kg.BW group (C4). The Betamethasone given through intra peritoneal and the ascorbic acid given subcutaneously for 30 days, then blood collection from animals for acting complete blood count (CBC), urea, creatinine, albumin, and liver enzyme tests. The results show blood urea, creatinine, albumin, bilirubin and the hepatic enzymes (ALT, AST, ALP) data showed increase in blood in treated guinea pigs (C3) after exposed to Betamethasone in 0.5 mg/kg. These increases returned to normal values upon treatment with Ascorbic Acid in the C4 group compared to the control group.
Pages: 24-27 | Views: 121 | Downloads: 46
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How to cite this article:
Alaa Najee Salih. Study of protective role of ascorbic acid against betamethasone in female guinea pigs (Cavia porcellus). Zool Entomol Lett 2024;4(2):24-27.
