Zoological and Entomological Letters
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P-ISSN: 2788-8428, E-ISSN: 2788-8436

2021, Vol. 1, Issue 1, Part A


In vitro anti-oxidant activity of phytochemical analysis and various human cancerous cell line using microtiter plate based assay Moringa oleifera leaf extract


Author(s): Azhagu Madhavan S, Ranjani R and Sripriya R

Abstract: Moringa oleifera leaves, bioactive compounds within are may possess cancer-selective ant proliferative properties. Past research has been directed with respect to this subject, however poor trial configuration because of absence of vital controls restricts the authenticity of anticancer cases. Moringa oleifera plant contains a numerous antioxidants, antibiotics and nutrients (vitamins and minerals) which makes it prospective for diverse biomedical applications. In vitro antioxidant. This mostly contributes to the antioxidant power of the extracts, which is affirmed by the IC50 values of the crude extracts in the Moringa oleifera. (A) DPPH scavenging activity (B) H2O2 scavenging activity (C) Nitric oxide scavenging activity (D) FRAP assay. The FRAP assay also exhibit a constant increase in reducing ability with increase in the concentration which is indicative of the extract’s antioxidant potential. In order for anticancer claims to be sufficient and yield the possibility of a future cancer treatment, Moringa oleifera leaves extract must not harm non-cancerous cells. The prevention and treatment of a series of chronic diseases including inflammatory diseases, neuro-dysfunctional diseases, diabetes, and cancers which will provide a reference for its possible application in the prevention and treatment of chronic diseases or health encouragement. The present study suggests that the hydro-alcoholic leaf extract of M. oleifera induces anticancer effect on K-562, DU-145 and HCT-15 cancer cells.

Pages: 38-43 | Views: 1017 | Downloads: 540

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How to cite this article:
Azhagu Madhavan S, Ranjani R, Sripriya R. In vitro anti-oxidant activity of phytochemical analysis and various human cancerous cell line using microtiter plate based assay Moringa oleifera leaf extract. Zool Entomol Lett 2021;1(1):38-43.

Zoological and Entomological Letters